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BPS Bioscience Inc.
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Cas9-Expressing HeLa Cell Pool

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產品型號78161

品       牌BPS Bioscience

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更新時間:2024-11-26 12:48:58瀏覽次數:158次

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●Purchase●DescriptionCas9(StreptococcuspyogenesCRISPRassociatedprotein9)isanendonucleaseenzymethat
Purchase
Description

Cas9 (Streptococcus pyogenes CRISPR associated protein 9) is an endonuclease enzyme that, when recruited to a specific DNA sequence by the sgRNA (single guide RNA), introduces a double stranded break into the DNA. This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the targeted gene. Cas9-expressing HeLa cells can be transduced or electroporated with sgRNA targeting a gene of interest to quickly generate knock-out cell pools or cell lines.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

Synonyms
SpCas9 cell pool, CRISPR cell pool, Cas9 cell pool, HeLa cell pool

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