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MIDLAND is primarily engaged in the custom manufacture and sale of synthetic DNA and RNA products. MIDLAND'S experience in custom oligonucleotide synthesis is unsurpassed in the biotechnology industry. For over 20 years, MIDLAND's products have been used by researchers worldwide.
The focus of the MIDLAND business plan is to be able to make a single oligonucleotide when a unique molecule is needed and then to be able to make hundreds or thousands of similar oligos as the successful project passes from a research idea to full-scale production.

We Specialize in Highly Modified Oligos!

PRICE LIST （3）

PRICES FOR MOST POPULAR SERVICES
DNA Synthesis	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
DNA Synthesis	$0.30（1）	$0.39/Base	$0.75/Base	$1.75/Base	$17.00/Base
96 Well Plate Orders（2）	$0.20（1）	$0.30/Base	$0.50/Base	$1.00/Base	N/A
Phosphorothioate DNA	N/A	N/A	$3.00/Base（2）	$4.00/Base（2）	$30.00/Base（2）
DNA Set-Up	$0.00	$0.00	$0.00	$0.00	$0.00
RNA Synthesis	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
RNA Synthesis	N/A	N/A	$9.00	$15.00/Base	Call
2'O-Methyl RNA	N/A	N/A	$9.00/Base	$15.00/Base	Call
RNA Set-Up	N/A	N/A	$15.00	$25.00	Call
Shipping	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
Shipping Charges	$15.00	$15.00	$15.00	$15.00	$15.00
Purifications	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
Gel Filtration	$0.00	$0.00	$0.00	$0.00	$0.00
AEHPLC	N/A	N/A	$90.00	$175.00	$250.00
RPHPLC	N/A	$30.00	$45.00	$90.00	$250.00
PAGE	N/A	$30.00	$125.00	$425.00	N/A
Cartridge	N/A	$25.00	$35.00	N/A	N/A
Modifications - 3' or 5'-End （4）	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
Biotin	N/A	$40.00	$50.00	$90.00	$450.00
Phosphate	N/A	$20.00	$25.00	$45.00	$200.00
5'-Amino C6	N/A	$20.00	$25.00	$40.00	$250.00
3'-Amino C7	N/A	$20.00	$25.00	$40.00	$250.00
Digoxigenin	N/A	$200.00	$210.00	$290.00	$950.00
Thiol Modifier C6 S-S	N/A	$150.00	$180.00	$225.00	$475.00
5'-Thiol C6	N/A	$60.00	$75.00	$100.00	$300.00
Internal Modifications （4）	20 nmole	50 nmole	200 nmole	1 mmole	10 mmole
dI	N/A	N/A	$12.00	$17.50	$50.00
dU	N/A	N/A	$14.00	$17.50	$50.00
Abasic	N/A	N/A	$120.00	$160.00	$420.00
2-Aminopurine	N/A	N/A	$160.00	$200.00	$450.00
8-Oxo-dG	N/A	N/A	$200.00	$250.00	$450.00

DNA Polymers
HOMOPOLYMERS	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
Poly dA （Polydeoxyadenylate）, sodium salt	P-2001	156.00	685.00	1370.00	2470.00	24000.00
Poly dC （Polydeoxycytidylate）, sodium salt	P-2002	145.00	640.00	1280.00	2400.00	23500.00
Poly dI （Polydeoxyinosinate）, sodium salt	P-2003	195.00	910.00	1800.00	3400.00	33000.00
Poly dT （Poldeoxythymidylate）, sodium salt	P-2004	150.00	650.00	1300.00	2200.00	21500.00
Poly dU （Polydeoxyuridylate）, sodium salt	P-2005	200.00	910.00	1800.00	3380.00	32000.00
DUPLEX POLYMERS	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
Poly d（A-T） . Poly d（A-T） Polydeoxy（adenylate-thymidylate）, sodium salt	P-2100	156.00	685.00	1370.00	2470.00	24000.00
Poly dA . Poly dT Polydeoxyadenylate . Polydeoxythymidylate, sodium salt	P-2300	156.00	685.00	1370.00	2470.00	24000.00
Poly d（I-C） . Poly d（I-C） Polydeoxy（inosinate-cytidylate）, sodium salt	P-2400	195.00	910.00	1800.00	3380.00	32000.00
Poly dI . Poly dC Polydeoxyinosinate . Polydeoxycytidylate, sodium salt	P-2410	195.00	910.00	1800.00	3380.00	32000.00

RNA Polymers
HOMORIBOPOLYMERS	NUMBER	25mg	100mg	500mg	1000mg	50 A₂₆₀U	250 A₂₆₀U
Poly rA （Polyadenylic acid）, potassium salt	P-3001	140.00	450.00	1800.00	3400.00	--	--
Poly rC （Polycytidylic acid）, potassium salt	P-3002	90.00	260.00	1200.00	2300.00	--	--
Poly rI （Polyinosinic acid）, potassium salt	P-3003	130.00	400.00	1600.00	3100.00	--	--
Poly rU （Polyuridylic acid）, potassium salt	P-3004	130.00	400.00	1600.00	3100.00	--	--
DUPLEX RIBOPOLYMERS	NUMBER	25mg	100mg	500mg	1000mg	50 A₂₆₀U	250 A₂₆₀U
Poly rA . Poly rU （Polyadenylic-Uridylic acid）, sodium salt	P-3100	135.00	330.00	1500.00	2700.00	--	--
Poly rI . Poly rC （Polyinosinic-cytidylic acid）, sodium salt	P-3101	140.00	450.00	1800.00	3400.00	--	--
Poly rA . 2 Poly rU Triple-Stranded Polymer, sodium salt	P-3102	170.00	650.00	1800.00	3300.00	130.00	620.00

OLIGOMERS

In addition to offering DNA and RNA polymers, Midland offers a full line of primers for molecular biological research. We offer the complete homologous series of oligo deoxythymidylates from p（dT）2 （thymine dinucleotide） through p（dT）36, as well as mixed p（dT）12-18 and p（dT）19-24. Additionally, a number of oligo dA, oligo dC, and oligo dG homologs are available. Please call for pricing for any of the oligo dN products; a few are listed below.

Click here to place order.

Oligomers
OLIGODEOXYADENYLATES-Non-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
dA₁₀, sodium salt	B-1010	45.00	210.00	400.00	770.00	7200.00
dA₁₂, sodium salt	B-1012	55.00	260.00	500.00	970.00	9200.00
dA₁₄, sodium salt	B-1014	65.00	310.00	600.00	1150.00	11000.00
dA₁₆, sodium salt	B-1016	70.00	340.00	650.00	1250.00	12000.00
dA₁₈, sodium salt	B-1018	70.00	340.00	650.00	1250.00	12000.00
OLIGODEOXYADENYLATES-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
p（dA）₂, ammonium salt	A-1002	18.00	75.00	143.00	240.00	2300.00
p（dA）₁₀, sodium salt	A-1010	47.00	183.00	360.00	700.00	6500.00
p（dA）_12-18, sodium salt	A-1218	47.00	183.00	360.00	700.00	6500.00
OLIGODEOXYCYTIDYLATES-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
p（dC）₁₀, sodium salt	C-1010	57.00	250.00	480.00	920.00	8900.00
p（dC）_12-18, sodium salt	C-1218	57.00	230.00	480.00	920.00	8900.00
OLIGODEOXYGUANYLATES-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
p（dG）₁₀, sodium salt	G-1010	57.00	230.00	--	--	--
p（dG）_12-18, sodium salt	G-1218	57.00	230.00	--	--	--
OLIGODEOXYTHYMIDYLATES-Non-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
dT₁₀, sodium salt	D-1010	37.00	170.00	320.00	610.00	5900.00
dT₁₂, sodium salt	D-1012	55.00	260.00	500.00	970.00	9200.00
dT₁₄, sodium salt	D-1014	65.00	310.00	600.00	1150.00	11000.00
dT₁₆, sodium salt	D-1016	70.00	340.00	650.00	1250.00	12000.00
dT₁₈, sodium salt	D-1018	70.00	340.00	650.00	1250.00	12000.00
dT_12-18, sodium salt	D-1218	39.00	190.00	370.00	720.00	7100.00
OLIGODEOXYTHYMIDYLATES-Phosphorylated	NUMBER	5 Units	25 Units	50 Units	100 Units	1000 Units
p（dT）₂, ammonium salt （Thymine Dinucleotide）	N-1002	18.00	75.00	143.00	240.00	2300.00
p（dT）₁₀, lithium salt	O-1010	39.00	190.00	370.00	720.00	7100.00
p（dT）_12-18, lithium salt	O-1218	39.00	190.00	370.00	720.00	7100.00
p（dT）₂, sodium salt （Thymine Dinucleotide）	P-1002	18.00	75.00	143.00	240.00	2300.00
p（dT）₃, sodium salt	P-1003	22.00	110.00	220.00	440.00	4400.00
p（dT）₄, sodium salt	P-1004	22.00	110.00	220.00	440.00	4400.00
p（dT）₅, sodium salt	P-1005	22.00	110.00	220.00	440.00	4400.00
p（dT）₆, sodium salt	P-1006	24.00	120.00	240.00	480.00	4800.00
p（dT）₇, sodium salt	P-1007	26.00	130.00	260.00	520.00	5200.00
p（dT）₈, sodium salt	P-1008	29.00	145.00	290.00	580.00	5800.00
p（dT）₉, sodium salt	P-1009	32.00	145.00	290.00	580.00	5800.00
p（dT）₁₀, sodium salt	P-1010	39.00	190.00	370.00	720.00	7100.00
p（dT）₁₁, sodium salt	P-1011	49.00	183.00	360.00	700.00	6500.00
p（dT）₁₂, sodium salt	P-1012	60.00	250.00	480.00	920.00	8900.00
p（dT）₁₃, sodium salt	P-1013	69.00	310.00	600.00	1150.00	11000.00
p（dT）₁₄, sodium salt	P-1014	69.00	310.00	600.00	1150.00	11000.00
p（dT）₁₆, sodium salt	P-1016	80.00	390.00	750.00	1450.00	14000.00
p（dT）₁₈, sodium salt	P-1018	80.00	390.00	750.00	1450.00	14000.00
p（dT）₃₆, sodium salt	P-1036	107.00	500.00	950.00	1800.00	17000.00
p（dT）_19-24, sodium salt	P-1119	89.00	420.00	800.00	1500.00	14500.00
p（dT）_12-18, sodium salt	P-1218	39.00	190.00	370.00	720.00	7100.00

TEMPLATE/PRIMERS
ITEM	CATALOG NO.	5 Units	25 Units	50 Units	100 Units	1000 Units
Poly rA ? Poly dT	P-4005	50.00	190.00	360.00	720.00	7000.00
Poly rA ? p（dT）₁₀	P-4010	50.00	190.00	360.00	720.00	7000.00
Poly rA ? p（dT）_12-18	P-4012	50.00	190.00	360.00	720.00	7000.00
Poly dA ? p（dT）₁₀	P-4110	50.00	190.00	360.00	720.00	7000.00
Poly dA ? p（dT））_12-18	P-4112	50.00	190.00	360.00	720.00	7000.00
Poly rC ? p（dG））_12-18	P-4210	50.00	190.00	360.00	720.00	7000.00
Poly dC ? p（dG））_12-18	P-4212	50.00	190.00	360.00	720.00	7000.00

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