BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.

The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]